Background

Animal and observational studies in humans suggest that deeper sleep is associated with slower progression of neurodegenerative processes. Several long-term studies will now investigate whether targeted enhancement of deep sleep in the context of Alzheimer’s or Parkinson’s disease can slow disease progression or even act preventively.

To enhance deep sleep, a non-invasive, non-pharmacological method of acoustic slow-wave sleep stimulation is used: playing tones synchronized with brain activity to strengthen slow-wave sleep.

To initiate, establish, and manage these studies operationally, the Department of Neurology at the University Hospital Zurich is seeking an engaged Clinical Trial Manager.

Main responsibilities

• Administrative and operational management of clinical studies in close coordination with the project leadership
  
• Development and maintenance of project and trial management systems
  
• Setup of electronic databases (e.g., REDCap)
  
• Planning and coordination of all study-related activities, including scheduling, resource planning, task delegation, and supervision of study staff
  
• Communication and coordination with collaboration partners and authorities
  
• Preparation and submission of study documents, as well as organization of necessary approvals and contracts
  
• Development and implementation of study processes, documentation, and training
  
• Establishment and monitoring of quality, data, and safety management systems
  
• Coordination of participant recruitment
  
• Ensuring study documentation and reporting to project leadership

Profile requirements:

• University degree (Master or PhD) in a medical, life science, or health science field
  
• Several years of experience in coordinating and conducting clinical studies (according to KlinV/KlinV-Mep) and solid knowledge of regulatory requirements, preferably with relevant training (e.g., CAS in Clinical Trial Management)
  
• Extensive experience in project management
  
• Excellent command of German (spoken and written) and good knowledge of English; knowledge of French or Italian is a plus
  
• Strong computer skills (MS Office) and experience with study databases (e.g., REDCap)
  
• Structured, independent working style, strong organizational skills, and a high degree of quality awareness
  
• Teamwork skills, strong communication abilities, and flexibility

What's offered

• Exciting, independent, and varied work with insights into the latest methods in clinical sleep research and biotechnology
  
• Participation in a highly motivated, interdisciplinary team at the Department of Neurology, University Hospital Zurich
  
• Interdisciplinary collaboration
  
• Public-law employment conditions of the University of Zurich
  
• As the position is funded through third-party projects, the employment is initially limited until the end of 2028 – with the possibility of extension within further projects

Application

Interested candidates are invited to send their application dossier (CV, cover letter, certificates, and contact details of two references) to Dr. Angelina Maric via the following email address:

schlafforschung@usz.ch